Tissue-Tek AutoSection® Automated Microtome


Tissue-Tek AutoSection® delivers the next level in precision sectioning.

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Tissue-Tek AutoSection® provides one-touch trimming and programmable sectioning with a host of built-in safety features. Tissue-Tek AutoSection® automatically orients the block to the blade edge, using patented sensing and automated  3-D specimen holder technology for precise XYZ orientation. It standardizes block orientation—even if the block was trimmed or sectioned on a different microtome—saving valuable tissue and technician time. With AutoTrim™, the Tissue-Tek AutoSection® trims blocks automatically in just seconds with one-touch operation. This tissue-preserving feature is optimized for Tissue-Tek® Paraform® Cassettes, although it also accommodates most common cassettes.

Multiple built-in safeguards make Tissue-Tek AutoSection® the leader in microtome user safety. One-touch trimming and sectioning eliminate repetitive hand wheel motions and reduce the risk of musculoskeletal disorders, while the sliding dispenser feature of Accu-Edge® blades eliminates direct handling of blades.

Tissue-Tek AutoSection® is the most accurate and precise microtome on the market as determined by laser measurements. And with programmable sectioning, it enables laboratories to implement standardized protocols for specific tissue or block types. Tissue-Tek AutoSection® also standardizes section thickness to help optimize advanced staining procedures such as IHC and ISH.


  • AutoAlign™ and AutoTrim™ technologies
  • One-touch operation to engage cutting modes
  • 16 user-defined trimming/sectioning programs
  • Up to 15 parameters for a variety of tissue protocols 
    (including block size, thickness, and speed)
  • LCD touch screen control panel
  • 3-D chuck/specimen holder
  • Wireless remote control
  • Multiple safety features
  • Optional hand wheel


Application: Sectioning of paraffin-embedded specimens for routine and research histology
Product Code: #5000
Dimensions: Centimeters (W x D x H): 38 x 67 x 44 
Inches (W x D x H): 15 x 26.4 x 17.4
Weight (with microtome): 55 kg/121 lb
Administrator access: Password protected
Section thickness: 0.5 - 100 microns
Trimming thickness: 1 - 200 microns
Retraction distance: No retraction, 20-100 microns
Sectioning speed: 10 - 450 mm/second
Trimming speed: 10 - 450 mm/second
Return speed: 10 - 450 mm/second
Maximum specimen size: 60 x 60 mm
Maximum vertical stroke: 122 mm
Maximum horizontal stroke: 10 mm
Number of presets: Up to 16 different presets
Number of macro program steps: Up to 16 steps
Number of user preferences: Up to 32 different preferences

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