Tissue-Tek VIP® 6 AI

THE First choice in tissue processing now with advanced infiltration

The Tissue-Tek VIP® 6 AI Vacuum Infiltration Processor continues with Sakura reliability and innovation to provide the first and only tissue processor with automated onboard preparation of mixed solutions, automatic in-process reagent exchange, and Tissue-Tek® iSupport™ remote monitoring, which allows for safe, high-quality processing while saving time.

For more information, click on the tabs below, contact your Sakura representative, write to mail@sakuraus.com, or call 1-800-725-8723 and press 1 for customer service.



Advanced Infiltration
Using advanced infiltration methods, the Tissue-Tek VIP® 6 AI was designed to provide high-quality tissue processing results for all tissue types, including fatty tissues.  The Tissue-Tek VIP® 6 AI is the first and only tissue processor on the market capable of automatically mixing specified reagents onboard to create mixed solutions, providing advanced infiltration of fatty tissues by enhancing dehydration and defatting without extending protocol times.  Including 3 new mixing mode options, bringing the total number of options to 10, the Tissue-Tek VIP® 6 AI is able to provide highly effective yet gentle agitation of the reagent in the retort for excellent reagent penetration of tissues.

Tissue Safety
The Solution Manager of the Tissue-Tek VIP® 6 AI monitors reagent levels during operation for safe and worry-free processing.  Providing fresh reagent from the 2 bulk reagent reservoirs during processing if needed, the Solution Manager ensures that the Tissue-Tek VIP® 6 AI offers the highest level of processing confidence both during the day when staff is available or overnight during autonomous operation. 

The Tissue-Tek VIP 6 AI arrives compatible with Tissue-Tek® iSupport™, Sakura’s advanced remote diagnostics technology platform. Meeting the high-level security standards of today’s laboratories’ IT infrastructures, the secure remote service ensures maximum uptime through fast reaction to instrument alerts by Sakura’s professional technical support team.
Keeping with Sakura’s tradition of continuous improvement that has led to an industry-leading reputation in reliability, the Tissue-Tek VIP® 6 AI is equipped with a newly designed reagent manifold, making it the most reliable and safe Tissue-Tek VIP processor ever.  The advanced reagent manifold system includes new fluid sensors offering an improved solution detecting function that helps safeguard against unexpected user errors to maintain the highest level of tissue quality and integrity. 

The Tissue-Tek VIP® 6 AI also delivers strongly on user convenience.  Providing in-process Automatic Solution Transfer of two reagents and the paraffin, manual maintenance is significantly reduced, saving both time and money.  The onboard paraffin waste container makes the exchange and proper disposal of used paraffin safe, clean, and easy.  Color-coded drain and fill ports simplify the safe exchange of reagents onto the instrument.  An LED-lit reagent cabinet allows for quick visual observation of reagent levels.  Simple, convenient operation combined with the familiarity of the Tissue-Tek VIP processor series reduces opportunities for errors and shortens the learning curve, supporting the lab’s ability to hit the ground running on the very first day after installation


10 mixing modes Effective yet gentle reagent agitation for excellent reagent penetration
2 bulk reservoirs Convenient additional storage of fresh reagent with each holding up to 10.4 L
Automatic onboard mixing of reagents Mixed reateng solutions enhance dehydration and defatting without extending protocols times, and automatically mixing specified reagents from the 2 bulk reservoirs onboard to create the mixed reagent solutions saves time and reduces opportunities for human error
Solution Manager Monitors reagent levels during operation and provides fresh reagent from the 2 bulk reagent reservoirs if needed for safe and worry-free processing
Automatic solution transfer Enables in-process transfer of up to two reagents and the paraffin to significantly reduce maintenance, saving both time and money
Paraffin waste container Makes the exchange and proper disposal of used paraffin safe, clean, and easy
Automatic bottle check Verifies that all bottles are properly connected BEFORE a run starts to prevent errors before they happen
Tissue-Tek® iSupport™ The secure remote service ensures maximum uptime through fast reaction to instrument alerts by Sakura's professional technical support team
Fume control system Advanced filtering combines a fume condenser system and 2 disposable activated carbon filters to eliminate noxious fumes
Automatic paraffin degassing Aspirates evaporated clearing agent from the paraffin oven, keeping the paraffin clean while filtering harmful fumes
Newly designed reagent manifold Includes new fluid sensors offering an improved solution detecting function that helps safefuard against unexpected user errors
Color-coded drain & fill ports Simplifies the safe exchange of reatents onto the instrument
Ergonomic retort latch with electronic interlock Seal, lock and protect the retort from being opened during operation simply and operable one-handed
Heated retort lid Eliminates retort condensation
Heated cleaning reagent station Profides excellent deparaffinization and cleaning of the retort between processes
High-resolution color touch screen Easy to see, operate, and monitor the instrument
LED-lit reagent cabinet Allows for quick visual observation of reagent levels
Up to 50 user-defined programs Offers plenty of versatility to created the processing program that is best suited for the needs of the laboratory
3 user-defined cleaning cycles Provides effective cleaning options for different workflows
150- or 300-cassette capacity configurations Flexible options for both small or large runs for efficient use of reagents
Two level options for password protection Complete instrument and information security with admin control over what screens or features are accessible to users
Optional xylene-free processing Allows for the use of less hazardous reagent alternatives


Product Code: 6040
Rated voltage and current: Single phase, AC 115V ± 10%, 50/60 Hz, 12 Amps
Dimensions: 61 (W) x 68 (D) x 133 (H) cm
24 (W) x 27 (D) x 52 (H) inches
Weight: 175 kg (386 lbs) (without accessories and reagents)
Process capacity: Up to 300 Tissue-Tek® Uni-Cassettes® 
Reagent Reservoirs: 14 bottles: up to  4.2 liters (Including waste and cleaning)
Paraffin reservoirs: 3 small:  up to 4.2 liters
1 large:  up to 5.6 liters
Internal bulk reservoirs: 2 reservoirs, 10.4 liters each
Level sensors: 4, ultrasonic
Display: 10.4 in., color LCD, touch screen
External interface: USB 1.1 connector (only compatible with type of USB supplied)
External alarm output terminal
UPS signal input terminals (power outage and low battery)
LAN Terminal

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