Genemed® Advanced Staining Reagents

Immunohistochemistry (IHC) reagents

When using IHC reagents, the Genemed antibody portfolio offers a broad range of primary antibodies suitable for immunohistochemistry (IHC) on formalin-fixed paraffin embedded tissue samples. We primarily focus on in vitro diagnostics (IVD), which includes antibodies, detection systems, and ancillary IHC reagents for clinical testing in the histopathology laboratory.

Genemed IHC products offer you innovation that can only come from a company whose focus since 1987 has been geared toward producing medically-relevant antibodies for clinical pathology.


Genemed offers primary antibodies with high affinity and specificity for in vitro diagnostic and research use. Our primary antibodies are optimized and titrated for immunohistochemistry (IHC) testing using human formalin-fixed, paraffin-embedded (FFPE) tissue sections along with the Genemed IHC detection systems and ancillary reagents.

74 primary antibodies found
Product Code: 60-0001-7 7mL RTU
61-0001 1mL concentrate
Clone: HHF35
Host Clonality: mouse monoclonal
Control Tissue: appendix, colon
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody recognizes all muscular actin isotypes. It labels myoepithelial, smooth muscle, skeletal, cardiac muscle cells and leiomyomas. It has been reported to react with pericytes and reactive myofibroblasts. Positive staining cells have been reported in some sarcomas, representing either myofibroblasts or pericytes components. Using this antibody with other myogenic markers such as smooth muscle actin, desmin and vimentin may be very helpful for differentiation of tumor from muscle origin. Clone HHF35 has been demonstrated to be a reliable marker for soft tissue tumors with muscle differentiation, i.e. leiomyomas, leiomyosarcomas, and rhabdomyosarcomas.
Product Code: 60-0088-7 7mL RTU
Host Clonality: rabit polyclonal
Control Tissue: embryonal cardinoma / fetal liver
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody is primarily used for identification of hepatocellular carcinomas and hepatoid tumors.  Furthermore, it can identify germ cell tumors of testis and ovary such as yolk sac tumor and embryonal cardinoma and may be useful when used in a panel of antibodies.
Product Code: 60-0096-7 7mL RTU
61-0096 1mL concentrate
Clone: 13H4
Host Clonality: rabbit monoclonal
Control Tissue: kidney, prostate, tonsil
Staining Pattern: granular, cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the Alpha Methylacyl Coenzyme A Racemase (AMACR) protein in the cytoplasm of epithelia in both normal and neoplastic cells.  AMACR is positive in cells of premalignant high-grade prostatic intraepitheliam neoplasia and prostate adenocarcinoma, but is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign hyperplasia.  It is a useful tool for identifying prostate cancer when used in a panel of antibodies.
Product Code: 60-0005-7 7mL RTU
61-0005 1mL concentrate
Clone: Bcl-2-100
Host Clonality: mouse monoclonal
Control Tissue: appendix, tonsil
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the Bcl-2 protein in the cytoplasm of B-cells in mantle zones, interfollicular T-cell areas, and a few cells in the germinal centers of lymphoid tissues and basal cells of epithelial tissues; it can stain both normal and neoplastic cells.  It is a useful tool for identifying follicular lymphomas, diffuse large cell lymphomas, and differentiating follicular lymphomas from reactive lymph nodes when used in a panel of antibodies.
Product Code: 60-0020-7 7mL RTU
61-0020 1mL concentrate
Host Clonality: rabbit polyclonal
Control Tissue: appendix
Staining Pattern: membranous, cytoplasmic
Regulatory Status: IVD, FDA Class I
In the gastrointestinal organs such as the appendix and colon, strong membranous and cytoplasmic staining of Cajal cells is observed in the muscularis propria. Membranous and cytoplasmic staining with this antibody is also observed in the neoplastic cells of gastrointestinal stromal tumors (GIST). It is a useful tool for differentiating between gastrointestinal stromal tumors and other intra-abdominal mesanchymal tumors when used in a panel of antibodies.
Product Code: 60-0142-7 7mL RTU
61-0142 1mL concentrate
Clone: SPan-1
Host Clonality: mouse monoclonal
Control Tissue: kidney, pancreas
Staining Pattern: membranous, cytoplasmic
Regulatory Status: IVD, FDA Class I
In a panel of antibodies, e.g. CK19, CK7, CK20, CA19-9, this antibody can be an aid for differential diagnosis of adenocarcinomas.
Product Code: 60-0105-7 7mL RTU
Clone: CALP
Host Clonality: mouse monoclonal
Control Tissue: appendix, breast
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the CD5 protein on the membrane of T-cells and subsets of B-cells found in the follicular mantle zones, bone marrow, and peripheral blood. It is useful for classifying and characterizing T-cell and B-cell neoplasms when used in a panel of antibodies.
 
Product Code: 60-0006-7 7mL RTU
61-0006 1mL concentrate
Host Clonality: rabbit polyclonal
Control Tissue: adrenal gland, appendix
Staining Pattern: cytoplasmic, nuclear
Regulatory Status: IVD, FDA Class I
This antibody is a useful marker for the identification of malignant mesothelioma of the epithelial type and for the differentiation of the malignancies from metastases of lung adenocarcinoma. Differential diagnosis is aided by the results from a panel of antibodies.
 
Product Code: 60-0008-7 7mL RTU
61-0008 1mL concentrate
Clone: GM003
Host Clonality: mouse monoclonal
Control Tissue: kidney, tonsil
Staining Pattern: membranous, cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the CD10 protein on the membrane and cytoplasm of early lymphoid progenitors, small subset of immature B-cells, proliferating B-cells, mature neutrophils and on various non-lymphoid cells in both normal and neoplastic cells. It is a useful tool for classifying Burkitt’s lymphoma, some follicular lymphoma, and renal cell carcinoma when used in a panel of antibodies.
 
Product Code: 60-0164-7 7mL RTU
61-0164 1mL concentrate
Clone: GR014
Host Clonality: rabbit monoclonal
Control Tissue: appendix, tonsil
Staining Pattern: membranous
Regulatory Status: IVD, FDA Class I
This antibody is useful in identification of B-cell lineage of majority of B-cell neoplasms but appears to be less useful in sub-classifying of B-cell neoplasms in histological material. It is a useful biomarker for identification of follicular dendritic cell tumors when used in a panel of antibodies.
 
Product Code: 60-0010-7 7mL RTU
61-0010 1mL concentrate
Clone: L26
Host Clonality: mouse monoclonal
Control Tissue: appendix, tonsil
Staining Pattern: membranous
Regulatory Status: IVD, FDA Class I
This antibody labels the CD20 protein on the membrane of B-cell precursors and B-cells in both normal and neoplastic tissue. It is a useful tool for classifying tumor cells of B-lymphocytic lineage when used in a panel of antibodies.
 
Product Code: 60-0162-7 7mL RTU
61-0162 1mL concentrate
Clone: GR013
Host Clonality: rabbit monoclonal
Control Tissue: tonsil
Staining Pattern: membranous, some cytoplasmic
Regulatory Status: IVD, FDA Class I
Positive staining of neoplastic cells is observed in some B-cell lymphomas, whereas mantle cell lymphomas are generally negative for this antibody. This antibody is a useful tool for identifying/classifying a range of leukemias and lymphomas when used in a panel of antibodies.
 
Product Code: 60-0011-7 7mL RTU
60-0011 1mL concentrate
Host Clonality: rabbit polyclonal
Control Tissue: tonsil
Staining Pattern: membranous
Regulatory Status: IVD, FDA Class I
This antibody labels the CD3 protein in the cell membrane of normal and neoplastic T-cells. CD3 is expressed in the majority of T-cell neoplasms and is often not expressed in non T-cell lymphoid malignancies. It is useful for classifying T-cell neoplasms when used in a panel of antibodies. It may also be used to highlight T-cell populations within a variety of tissues.
 
Product Code: 60-0007-7 7mL RTU
61-0007 1mL concentrate
Clone: Ber-H2
Host Clonality: mouse monoclonal
Control Tissue: Hodgkin’s lymphoma, tonsil
Staining Pattern: membranous, cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels CD30 protein on the membrane and cytoplasm of scattered large activated B- and T-lymphocytes of tonsil, lymph nodes, the spleen and thymus in both normal and neoplastic tissue. The antibody labels the CD30 protein in normal and neoplastic cells, such as Hodgkin and Reed-Sternberg cells and anaplastic large-cell lymphoma cells (ALCL). CD30 positive staining may aid in identifying of classical Hodgkin’s lymphoma and ALCL when used in a panel of antibodies.
 
Product Code: 60-00072-7 7mL RTU
61-0072 1mL concentrate
Clone: GM006
Host Clonality: mouse monoclonal
Control Tissue: liver, tonsil
Staining Pattern: mainly membranous, some cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the CD31 protein on the membrane, and sometimes cytoplasm, of endothelial cells in both normal and neoplastic cells. It is a useful tool for identifying vascular disorder, e.g. angiosarcoma, and evaluating vascularization of tumors when used in a panel of antibodies.
 
Product Code: 60-0012-7 7mL RTU
61-0012 1mL concentrate
Clone: QBend10
Host Clonality: mouse monoclonal
Control Tissue: appendix, liver
Staining Pattern: membranous
Regulatory Status: IVD, FDA Class I
This antibody labels the CD34 protein on the membrane of hematopoietic progenitor cells, capillary endothelial cells, rare glial cells in nervous tissues, and embryonic fibroblasts in both normal and neoplastic tissue. It is a useful tool for classifying vascular and lymphatic tumors, and for sub-classifying leukemia when used in a panel of antibodies.
 
Product Code: 60-0138-7 7mL RTU
61-0138 1mL concentrate
Clone: GR009
Host Clonality: rabbit monoclonal
Control Tissue: brain, liver, tonsil
Staining Pattern: membranous
Regulatory Status: IVD, FDA Class I
This antibody labels the CD45 protein on the membrane of the leucocytes including lymphocytes, macrophages, and granulocytes in both normal and neoplastic tissue.  CD45 is detected in a large majority of hemotopoietic-lymphoid neoplasms, i.e. leukemia and malignant lymphomas.  Certain types of lymphoid neoplasms may lack CD45 cxpression (i.e. Hodgkin's disease, some T-cell lymphomas, and some leukemia).  It may be useful when used in a panel of antibodies.
Product Code: 60-0013-7 7mL RTU
61-0013 1mL concentrate
Clone: UCHL-1
Host Clonality: mouse monoclonal
Control Tissue: tonsil
Staining Pattern: membranous
Regulatory Status: IVD, FDA Class I
This antibody is a useful tool for identifying T-cell lymphomas, and for the differentiation of low grade B-cell and T-cell lymphomas when used in a panel of antibodies.
Product Code: 60-0183-7 7mL RTU
61-0183 1mL concentrate
Clone: GR020
Host Clonality: rabbit monoclonal
Control Tissue: tonsil
Staining Pattern: membranous, some cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the CD5 protein on the membrane of T-cells and subsets of B-cells found in the follicular mantle zones, bone marrow, and peripheral blood.  It is useful for classifying and characterizing T-cell and B-cell neoplasms when used in a panel of antibodies.
Product Code: 60-0062-7 7mL RTU
61-0062 1mL concentrate
Clone: 123C3
Host Clonality: mouse monoclonal
Control Tissue: appendix, tonsil
Staining Pattern: membranous, cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody may be used in the differential diagnosis of NK-cell lymphoma (CD56+/-) vs. other lymphomas (CD56-(+)), multiple myeloma (CD56+) vs. lympho-plasmacytic lymphoma, reactive plasmacytosis and monoclonal gammopathy of undetermined significance (MGUS) (CD56-(+)), in myeloid leukemic cells (CD56+) vs. normal myeloid cells (CD56-), non- papillary thyroid tumors (CD56+) vs. papillary thyroid carcinoma (CD56-) and schwannoma (CD56+) vs. neurofibroma (CD56-) when used in a panel of antibodies.
 
Product Code: 60-0184-7 7mL RTU
61-0184 1mL concentrate
Clone: GR021
Host Clonality: rabbit monoclonal
Control Tissue: brain, tonsil
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the CD68 protein on the cytoplasm of different types of macrophages of monocyte lineage, myeloid precursor cells in the bone marrow, some non-hemotopoietic tissues such as Kupffer cells in liver and cells in the renal glomeruli and tubules.  It is a useful tool for classifying neoplasms of myeloid and macrophage/monocyte origin when used in a panel of antibodies.
Product Code: 60-0182-7 7mL RTU
61-0182 1mL concentrate
Clone: GR019
Host Clonality: rabbit monoclonal
Control Tissue: colon, tonsil
Staining Pattern: membranous, cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the CD79a protein on the membrane and cytoplasm of select B-cells and T-lymphoblasts in normal and neoplastic tissue. It is a useful tool for classifying B-cell neoplasms and Hodgkin’s lymphoma when used in a panel of antibodies.
 
Product Code: 60-0124-7 7mL RTU
Clone: C8/144B
Host Clonality: mouse monoclonal
Control Tissue: tonsil
Staining Pattern: mainly membranous
Regulatory Status: IVD, FDA Class I
This antibody labels the CD8 protein on the membrane of T-cells in both normal and neoplastic tissue. It is a useful tool for classifying T-cell neoplasms and differentiating between cytotoxic and helper T-cells when used in a panel of antibodies.
 
Product Code: 60-0186-7 7mL RTU
61-0186 1mL concentrate
Clone: GR023
Host Clonality: rabbit monoclonal
Control Tissue: pancreas, tonsil
Staining Pattern: nuclear
Regulatory Status: IVD, FDA Class I
This antibody labels the CDX2 protein in epithelial cells from the duodenum to the rectum, including the pancreas and biliary tract.  It stains both normal and neoplastic cells. It is a useful tool for identifying and classifying adenocarcinomas and neuroendocrine tumors of the gastrointestinal tract when used in a panel of other antibodies.
Product Code: 60-0014-7 7mL RTU
61-0014 1mL concentrate
Clone: COL-1
Host Clonality: mouse monoclonal
Control Tissue: appendix, liver
Staining Pattern: membranous, cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the Carcinoembryonic Antigen (CEA) protein on the membrane and in the cytoplasm of both, normal and neoplastic cells, in the colon and a variety of other tissues. It is a useful tool for classifying adenocarcinomas, especially in the gastrointestinal tract, including colon and pancreatic adenocarcinomas. It is also a useful tool for classifying secretory meningioma and medullary carcinomas of the thyroid when used in a panel of antibodies.
Product Code: 60-0015-7 7mL RTU
61-0015 1mL concentrate
Host Clonality: rabbit polyclonal
Control Tissue: appendix, pancreas
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the Chromogranin A protein in the cytoplasm of neuroendocrine cells in both normal and neoplastic tissue. Moderate to strong granular cytoplasmic staining of neuroendocrine cells within the epithelial surface is observed in gastrointestinal organs; granular cytoplasmic staining is also seen in axons and perikarya of neurons and ganglion cells in the submucosa, whereas epithelial cells and muscle cells are negative. This antibody may be useful in the identification of neuroendocrine tumors when used in a panel of antibodies.
Product Code: 60-0090-7 7mL RTU
61-0090 1mL concentrate
Clone: GR005
Host Clonality: rabbit monoclonal
Control Tissue: tonsil
Staining Pattern: nuclear
Regulatory Status: IVD, FDA Class I
This antibody labels the Cyclin D1 protein in both normal and neoplastic cells. It is a useful tool for classifying mantle cell lymphomas and breast carcinoma when used in a panel of antibodies.
Product Code: 60-0022-07 7mL RTU
61-0022 1mL concentrate
Clone: AE1/AE3
Host Clonality: mouse monoclonal antibody cocktail
Control Tissue: esophagus, liver
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody cocktail labels cytokeratin proteins in the cytoplasm of normal and neoplastic cells. It is a useful tool for classifying tumors of epithelial origin and undifferentiated carcinomas when used in a panel of antibodies.
Product Code: 60-0017-7 7mL RTU
61-0017 1mL concentrate
Clone: CD-10
Host Clonality: mouse monoclonal
Control Tissue: colon, liver
Staining Pattern: membranous, cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the cytokeratin 18 (CK18) protein. It reacts with a wide variety of neoplastic tissues such as gastrointestinal tract, lung, and breast tumors. It does not react with tumor cells of nonepithelial origin such as glioma, melanoma and osteosarcoma. It also does not react with stratified squamous epithelium on most squamous cell carcinomas. This antibody may be useful when used in a panel of antibodies.
Product Code: 60-0163-7 7mL RTU
Clone: A53-B/A2.26
Host Clonality: mouse monoclonal
Control Tissue: esophagus
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the Cytokeratin 19 (CK19) protein in the cytoplasm of a variety of epithelium (colon, stomach, pancreas, biliary tract, liver and breast) in both normal and neoplastic tissue. It is a useful tool for determining thyroid carcinoma of papillary type although it is positive in 50-60% of follicular carcinoma when used in a panel of antibodies.
Product Code: 60-0018-7 7mL RTU
61-0018 1mL concentrate
Clone: Ks20.8
Host Clonality: mouse monoclonal
Control Tissue: appendix, liver
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the cytokeratin 20 (CK20) protein in the cytoplasm of mature enterocytes and goblet cells of the gastric and intestinal mucosa in both normal and neoplastic tissue. Most colon adenocarcinomas, mucinous ovarian tumors, transitional cell and Merkel-cell carcinomas, gastric adenocarcinomas, bile system, and pancreas are CK20 positive. Most squamous cell carcinomas and adenocarcinomas from breast, endometrium, lung, and prostate may be CK20 negative, as well as non-mucinous tumors of the ovary and small-cell lung carcinomas.  May be a useful tool when used in a panel of other antibodies.
Product Code: 60-0174-7 7mL RTU
61-0174 1mL concentrate
Clone: GM028
Host Clonality: mouse monoclonal
Control Tissue: esophagus
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the high molecular weight (HMW) cytokeratin (CK5) protein in both normal and neoplastic cells. Cytoplasmic staining is observed in stratified squamous epithelia, and in basal cells of complex epithelia. Simple epithelia and nonepithelial cells are negative. It is a useful tool for classifying squamous cell carcinoma, distinguishing malignant mesothelioma from lung adenocarcinoma, and determining breast and prostate malignancies when used in a panel of antibodies.
Product Code: 60-0016-7 7mL RTU
61-0016 1mL concentrate
Clone: D5/16B4
Host Clonality: mouse monoclonal
Control Tissue: esophagus, liver
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody is useful for classifying squamous cell carcinoma, distinguishing malignant mesothelioma from lung  adenocarcinoma, and determining breast and prostate malignancies when used in a panel of antibodies.
Product Code: 60-0019-7 7mL RTU
61-0019 1mL concentrate
Clone: OV-TL 12/30
Host Clonality: mouse monoclonal
Control Tissue: lung, pancreas
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the cytokeratin 7 (CK7) protein in the cytoplasm of most ductal, glandular, and transitional in both normal and neoplastic cells. It is a useful tool for classifying adenocarcinomas of lung, breast, endometrium, thyroid gland, ovary, and chromophobe renal cell carcinomas when CK7 is positive and when it is used in a panel of antibodies. It is a useful tool for classifying colonic and prostate lineage tumors when CK7 is negative and when it is in with a panel of antibodies.
Product Code: 60-0025-7 7mL RTU
61-0025 1mL concentrate
Clone: 34bE12
Host Clonality: mouse monoclonal
Control Tissue: esophagus, liver, prostate
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody is useful for differentiating benign prostate gland from prostate adenocarcinoma when used in a panel of antibodies. Monoclonal antibody clone 34bE12 can be used for the demonstration of high molecular weight cytokeratinin the basal cells of prostate specimens, but due to cross-reaction to low molecular weight cytokeratin in e.g. breast epithelial cells/breast carcinoma it cannot be recommended as a general marker for high molecular weight cytokeratin. This is a useful tool when used in a panel of antibodies.
Product Code: 60-0077-7 7mL RTU
61-0077 1mL concentrate
Clone: GM007
Host Clonality: mouse monoclonal
Control Tissue: appendix
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the desmin protein in both normal and neoplastic cells. It is a useful tool for subtyping undifferentiated and pleomorphic tumors when used in a panel of antibodies.
Product Code: 60-0028-7 7mL RTU
61-0028 1mL concentrate
Clone: GM016
Host Clonality: mouse monoclonal
Control Tissue: colon, liver
Staining Pattern: membranous
Regulatory Status: IVD, FDA Class I
This antibody is useful in distinguishing adenocarcinoma from mesothelioma and in the differentiation of ductal form lobular breast cancer when used in a panel of antibodies.
Product Code: 60-0030-7 7mL RTU
61-0030 1mL concentrate
Clone: GM008
Host Clonality: mouse monoclonal
Control Tissue: tonsil
Staining Pattern: membranous, cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the Epithelial Membrane Antigen (EMA) protein on the membrane and cytoplasm of the apical surface of secretory glandular epithelial cells in both normal and neoplastic tissue. It is a useful tool for identifying adenocarcinomas derived from secretory epithelia such as metastases of breast carcinoma. It is also a useful tool for identifying malignant mesothelioma, renal cell carcinomas, and meningiomas when used in a panel of antibodies.
Product Code: 60-0190-7 7mL RTU
61-0190 1mL concentrate
Clone: VU-1D9
Host Clonality: mouse monoclonal
Control Tissue: appendix, kidney, tonsil
Staining Pattern: membranous, cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the Epithelial Cell Adhesion Molecule (EpCAM) protein on the membrane and cytoplasm of epithelial cells in both normal and neoplastic cells. It is a useful tool for differentiating adenocarcinoma from malignant mesothelioma when used in a panel of antibodies.
Product Code: 60-0133-7 7mL RTU
Clone: 9C4
Host Clonality: mouse monoclonal
Control Tissue: papillary or follicular carcinoma of thyroid
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody is a useful tool in differentiating between benigh and malignant thyroid neoplasms.  It is a also a useful tool in identifying anaplastic large cell lymphoma when used in a panel of antibodies.
Product Code: 60-0032-7 7mL RTU
61-0032 1mL concentrate
Host Clonality: rabbit polyclonal
Control Tissue: brain
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
The antibody labels Glial Fibrillary Acidic Protein (GFAP) and is a useful tool for the identification of astrocytes in the CNS under normal and pathological conditions. In stomach, G-cells show a moderate to strong cytoplasmic staining, whereas epithelial cells are negative. Cytoplasmic staining is observed in neoplastic cells of gastrin-secreting neuroendocrine tumors. This antibody may be useful in the identification of gastric neuroendocrine tumors when used in a panel of antibodies.
Product Code: 60-0125-7 7mL RTU
61-0125 1mL concentrate
Host Clonality: rabbit polyclonal
Control Tissue: germ cell tumor, chorionic cardinoma
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
The antibody labels hCG containing cells and may be used for the demonstration of trophoblastic elements, e.g. in germ cell tumors.  The antibody cross-reacts with human luteinizing hermons (LH).  This cross-reaction will not cause misinterpretation for IHC use.  This antibody may be a useful tool when used in a panel of other antibodies.
Product Code: 60-0039-7 7mL RTU
61-0039 1mL concentrate
Clone: 2D11-H5
Host Clonality: mouse monoclonal
Control Tissue: pancreas
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody may be useful for identification of beta cells in normal pancreas and in tumors of beta cell origin, such as insulinoma, and distinguish that from other endocrine tumors of the pancreas.  This antibody may be a useful tool when used in a panel of antibodies.
Product Code: 60-0085-7 7mL RTU
61-0085 1mL concentrate
Host Clonality: rabbit polyclonal
Control Tissue: tonsil
Staining Pattern: membranous, cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody is useful for classifying B-cell lymphomas and myelomas when used in a panel of antibodies.
Product Code: 60-0078-7 7mL RTU
61-0078 1mL concentrate
Clone: GM010
Host Clonality: mouse monoclonal
Control Tissue: tonsil
Staining Pattern: nuclear
Regulatory Status: IVD, FDA Class I
This antibody labels the Ki67 protein in the nucleus of both normal and neoplastic cells. It is a useful tool for assessing proliferative activity of various tumors when used in a panel of antibodies.
Product Code: 60-0068-7 7mL RTU
61-0086 1mL concentrate
Host Clonality: rabbit polyclonal
Control Tissue: tonsil
Staining Pattern: membranous, cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody is useful for classifying B-cell lymphomas and myelomas when used in a panel of antibodies.
Product Code: 60-0113-7 7mL RTU
Host Clonality: rabbit polyclonal
Control Tissue: tonsil
Staining Pattern: membranous
Regulatory Status: IVD, FDA Class I
This antibody labels laminin, which is present in the basement membrane. The antibody may be useful in the characterization of basement membrane preservation, e.g. in breast cancer and adenocarcinomas of the lung when used in a panel of antibodies. Laminins have been found to promote cell adhesion, migration, protease activity, proliferation, tumor growth, angiogenesis and metastasis.
 
Product Code: 60-0118-7 7mL RTU
61-0118 1mL concentrate
Host Clonality: rabbit polyclonal
Control Tissue: tonsil
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody is an important marker that may demonstrate the myeloid or monocytic nature of acute leukemia. It may aid in the identification of histiocytic neoplasias and classifying lymphoproliferative disorders when used in a panel of antibodies.
Product Code: 60-0092-7 7mL RTU
61-0092 1mL concentrate
Clone: A103
Host Clonality: mouse monoclonal
Control Tissue: normal skin, kidney
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the melan A protein in the cytoplasm of skin, melanocytes and steroid producing cells in both normal and neoplastic tissue. It is a useful tool for identifying melanomas when used in a panel of antibodies.
Product Code: 60-0042-7 7mL RTU
61-0042 1mL concentrate
Clone: HMB45
Host Clonality: mouse monoclonal
Control Tissue: melanoma
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the melanosome protein in the cytoplasm of melanocytes in both normal and neoplastic cells. It is a useful tool for classifying melanomas and melanocytic lesions and differentiating metastatic melanomas from other poorly differentiated tumors when used in a panel of antibodies.
Product Code: 60-0158-7 7mL RTU
61-0158 1mL concentrate
Clone: GM024
Host Clonality: mouse monoclonal
Control Tissue: colon, tonsil
Staining Pattern: nuclear
Regulatory Status: IVD, FDA Class I
This antibody labels the MutS homolog 6 (MSH6) protein in the nucleus of proliferating cells in both normal and neoplastic cells and does not label colon adenocarcinoma with complete loss of MSH6 expression. MSH6 is a useful tool for classifying tumors of the gastrointestinal tract, including associated extra colonic cancers such as endometrial and prostate cancers, when used in a panel of antibodies.
Product Code: 60-0160-7 7mL RTU
61-0160 1mL concentrate
Clone: Nd-2
Host Clonality: mouse monoclonal
Control Tissue: stomach
Staining Pattern: cytoplasm and perinuclear
Regulatory Status: IVD, FDA Class I
This marker is not expressed in normal pancreas but is expressed by most pancreatic ductal adenocarcinomas. MUC5AC is expressed also by endocervical adenocarcinomas and a variable number of tumors of the gastrointestinal tract. Together in a panel of antibodies, MUC5AC may be useful for identification of pancreatic carcinoma and pre-cancerous changes and differentiation of intestinal metaplasia.
Product Code: 60-0079-7 7mL RTU
61-0079 1mL concentrate
Clone: GM011
Host Clonality: mouse monoclonal
Control Tissue: colon, tonsil
Staining Pattern: nuclear
Regulatory Status: IVD, FDA Class I
This antibody labels the MutL homolog 1 (MLH1) protein in the nucleus of normal proliferating cells in both normal and neoplastic tissues and does not stain colon adenocarcinoma with complete loss of MLH1 expression. MLH1 is a useful tool for classifying tumors of the gastrointestinal tract, including associated extra colonic cancers such as endometrial and prostate cancers, when used in a panel of antibodies.
Product Code: 60-0105-7 7mL RTU
Clone: 5.8A
Host Clonality: mouse monoclonal
Control Tissue: rhabdomyosarcoma
Staining Pattern: nuclear
Regulatory Status: IVD, FDA Class I
The antibody labels the nuclei of myoblasts in developing skeletal muscle tissue, and the majority of rhabdomyosarcomas of various histological subtypes.  This antibody may be useful when used in a panel of antibodies.
 
Product Code: 60-0149-7 7mL RTU
61-0149 1mL concentrate
Clone: F5D
Host Clonality: mouse monoclonal
Control Tissue: rhabdomyosarcoma
Staining Pattern: nuclear
Regulatory Status: IVD, FDA Class I
This antibody labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may present in Wilm’s tumor. This antibody may be useful when used in a panel of antibodies.
 
Product Code: 60-0048-7 7mL RTU
61-0048 1mL concentrate
Clone: 2F11
Host Clonality: mouse monoclonal
Control Tissue: appendix, brain
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody is a useful tool for the identification of tumors with neuronal differentiation and Hirschsprung’s disease when used in a panel of antibodies.
 
Product Code: 60-0050-7 7mL RTU
61-0050 1mL concentrate
Clone: BP53.12
Host Clonality: mouse monoclonal
Control Tissue: colon, tonsil
Staining Pattern: nuclear
Regulatory Status: IVD, FDA Class I
This antibody labels the p53 protein in the nucleus in neoplastic cells. It is a useful tool for classifying tumors of all cell lineages when used in a panel of antibodies.
Product Code: 60-0074-7 7mL RTU
Clone: 4B1E12
Host Clonality: mouse monoclonal
Control Tissue: placenta, prostate, tonsil
Staining Pattern: nuclear
Regulatory Status: IVD, FDA Class I
This antibody is a useful tool for differentiating squamous, urothelial, and myoepithelial neoplasms when used in a panel of antibodies.
Product Code: 60-0093-7 7mL RTU
61-0093 1mL concentrate
Clone: GR024
Host Clonality: rabbit monoclonal
Control Tissue: colon, tonsil
Staining Pattern: nuclear
Regulatory Status: IVD, FDA Class I
This antibody is useful for subtyping lymphomas and lymphatic leukemia in a panel of antibodies. Paired box 5 (PAX5) is expressed in B-cell non-Hodgkin’s lymphoma (B-NHL), Hodgkin’s lymphoma (HL) and neuroendocrine tumors.
 
Product Code: 60-0054-7 7mL RTU
61-0054 1mL concentrate
Clone: PC10
Host Clonality: mouse monoclonal
Control Tissue: tonsil
Staining Pattern: nuclear
Regulatory Status: IVD, FDA Class I
This antibody is useful for identifying the expression of Proliferating Cell Nuclear Antigen (PCNA) or cyclin or polymerase delta auxiliary protein. It is elevated in the nucleus during late G1 phase immediately before the onset of DNA synthesis, becoming maximal during S-phase and declining during G2 and M phases. PCNA may act as an auxiliary protein of DNA polymerase-delta to play a fundamental role in the initiation of cell proliferation and may be useful when used in a panel of antibodies.
 
Product Code: 60-0139-7 7mL RTU
61-0139 1mL concentrate
Clone: GM022
Host Clonality: mouse monoclonal
Control Tissue: placenta
Staining Pattern: membranous, cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody is a useful tool for the identification of germ cell tumors (e.g. seminomas) and for the identification desmoplastic small round cell tumors (a soft tissue sarcoma). Placental Alkaline Phosphatase (PLAP) is a highly sensitive marker for the majority of embryonal carcinomas, and endodermal sinus tumors of the testis. Differential identification is aided by the results from a panel of antibodies. This antibody may be used along with EMA and cytokeratin [AE1/AE3] to distinguish germ cell tumors from somatic tumors.
 
Product Code: 60-0100-7 7mL RTU
Clone: D2-40
Host Clonality: mouse monoclonal
Control Tissue: appendix, tonsil
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody is useful for differentiating between malignant mesotheliomas and adenocarcinomas, identifying seminomas, and visualizing lymphatic vessels and lymphatic invasion of primary tumors when used in a panel of antibodies.
 
Product Code: 60-0058-7 7mL RTU
61-0058 1mL concentrate
Host Clonality: rabbit polyclonal
Control Tissue: appendix, prostate hyperplasia
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody which is reactive with the Prostate Specific Antigen (PSA) is a useful tool for identification of adenocarcinoma of the prostate in metastatic sites and for differentiating prostate adenocarcinoma from urothelial carcinoma. This antibody may be useful when used in a panel of antibodies.
 
Product Code: 60-0104-7 7mL RTU
61-0104 1mL concentrate
Clone: PASE/4LJ
Host Clonality: mouse monoclonal
Control Tissue: prostate
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody is a useful tool for the identification of normal prostatic tissue and prostatic carcinoma when used in a panel of antibodies.
 
Product Code: 60-0061-7 7mL RTU
61-0061 1mL concentrate
Host Clonality: rabbit polyclonal
Control Tissue: appendix, tonsil
Staining Pattern: cytoplasmic and nuclear
Regulatory Status: IVD, FDA Class I
This antibody labels the S100 protein in the cytoplasm of glial cells of nervous system, melanocytes, chondrocytes, and adipocytes. It is a useful tool for classifying tumors in nervous system and differentiating melanomas and nerve sheath tumors from carcinomas when used in a panel of antibodies.
Product Code: 60-0001-7 7mL RTU
61-0001 1mL concentrate
Clone: 1A4
Host Clonality: mouse monoclonal
Control Tissue: appendix, liver
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
Using this antibody with other myogenic markers such as muscle actin, desmin and vimentin is helpful for differentiation of tumor from muscle origin when used in a panel of antibodies. It is a useful marker for the identification for soft tissue tumors with muscle differentiation, i.e. leiomyomas and leiomyosarcomas. It is a useful marker for distinction of benign proliferative lesions of the breast from neoplastic proliferations.
Product Code: 60-0122-7 7mL RTU
61-0122 1mL concentrate
Clone: GR007
Host Clonality: rabbit monoclonal
Control Tissue: colon, pancreas
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
In the appendix and colon, moderate to strong cytoplasmic staining of axons is observed in the Auerbach’s and Meissner’s plexus, and at least moderate cytoplasmic staining of endocrine cells of the mucosal tissue. Cytoplasmic staining is also observed in neuronal and neuroendocrine tumors. This antibody is a useful tool for identifying and classifying neuronal and neuroendocrine tumors when used in a panel of antibodies.
 
Product Code: 60-0115-7 7mL RTU
Host Clonality: rabbit polyclonal
Control Tissue: thymus
Staining Pattern: nuclear
Regulatory Status: IVD, FDA Class I
This antibody has value in classification of malignant lymphomas and acute leukemias, particularly for the identification of pre-B and pre-T acute lymphoblastic leukemia (ALL) / lymphoblasitic lymphoma (LBL).  The intensity of Terminal Deoxyribo-nucleotidyl Transferase (TdT) expression is important since weak expression of TdT does not strongly support the diagnosis of ALL and LBL.  This antibody may be useful when used in a panel of antibodies.
Product Code: 60-0064-7 7mL RTU
61-0064 1mL concentrate
Clone: 2H11/6E1
Host Clonality: mouse monoclonal
Control Tissue: thyroid
Staining Pattern: cytoplasmic and extracellular
Regulatory Status: IVD, FDA Class I
This antibody may be useful in the identification of well-differentiated thyroid carcinomas and metastatic thyroid carcinomas. It is expressed in most papillary and follicular thyroid carcinoma when used in a panel of antibodies
Product Code: 60-0065-7 7mL RTU
61-0065 1mL concentrate
Clone: 8G7G3/1
Host Clonality: mouse monoclonal
Control Tissue: lung, thyroid
Staining Pattern: nuclear
Regulatory Status: IVD, FDA Class I
This antibody labels the Thyroid Transcription Factor-1 (TTF-1) protein in the nucleus of follicular epithelial cells in normal thyroid and thyroid tumors, in nuclei of type II pneumocytes, Clara cells, and basal cells of terminal bronchioles in normal lung and lung adenocarcinomas. It is a useful tool for differentiating primary versus metastatic tumors in lung and thyroid when used in a panel of antibodies.
 
Product Code: 60-0170-7 7mL RTU
Clone: GR016
Host Clonality: rabbit monoclonal
Control Tissue: small intestine or colonic mucosa
Staining Pattern: membranous and cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody may also be a useful marker of gastrointestinal tumors particularly those from the colon and stomach, and pancreas. Villin may be a useful marker also for some neuroendocrine carcinomas and ovarian adenocarcinomas when used in a panel of antibodies.
 
Product Code: 60-0066-7 7mL RTU
61-0066 1mL concentrate
Clone: V9
Host Clonality: mouse monoclonal
Control Tissue: tonsil
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody labels the vimentin antigen in the cytoplasm of mesenchymal cells such as fibroblasts, smooth muscle cells and endothelium in both normal and neoplastic tissue. It is a useful tool for classifying neoplastic tissues of mesenchymal origin such as soft tissue tumors when used in a panel of antibodies.
Product Code: 60-0109-7 7mL RTU
61-0109 1mL concentrate
Host Clonality: rabbit polyclonal
Control Tissue: tonsil
Staining Pattern: cytoplasmic
Regulatory Status: IVD, FDA Class I
This antibody must be used in conjunction with other more sensitive markers of endothelial cells (e.g. CD34 and CD31) for identifying anglosarcomas.  There is overlap between the expression of Von Willebrand Factor (VWF) in vascular and lymphatic endothelium.  This antibody may be helpful when used in a panel of antibodies.
Product Code: 60-0135-7 7mL RTU
Clone: 6F-H2
Host Clonality: mouse monoclonal
Control Tissue: fallopian tube, kidney
Staining Pattern: nuclear
Regulatory Status: IVD, FDA Class I
This antibody is particularly useful for distinguishing malignant mesothelioma and ovarian serous carcinoma from nonserous carcinomas. Wilms Tumor 1 (WT1) is also applicable for the differential diagnostic of small cell childhood tumors when used in a panel of antibodies.
 

Buffers

Product code

Product name and quantity

10-0176

Genemed® SSC Stringent Wash Buffer; RTU, 1 bottle, 3.8 L


Regulatory status:  IVD, FDA class I

Ancillary

Product code

Product name and quantity

10-0177-15

Genemed® CISH Amplification Linker; RTU, 1 bottle, 15 mL

 
Regulatory status:  IVD, FDA class I

Probes

Product code

Product name and quantity

70-0027-15

Genemed® CISH Kappa Probe; RTU, 1 bottle, 15 mL

70-0028-15

Genemed® CISH Lambda Probe; RTU, 1 bottle, 15 mL

70-0029-15

Genemed® CISH EBER Probe; RTU, 1 bottle, 15 mL

70-0030-15

Genemed® CISH mRNA Positive Control Probe; RTU, 1 bottle, 15 mL

70-0031-15

Genemed® CISH mRNA Negative Control Probe; RTU, 1 bottle, 15 mL

  
Regulatory status:  ASR

The Genemed detection kits, using IHC reagents, offer highly sensitive detection systems for immunohistochemistry applications. They are easy-to-use and provide strong staining with the lowest possible background.

Genemed® Power-Stain™ 1.0 Poly HRP DAB Kit for Mouse + Rabbit

This kit is a non-biotin system and utilizes a Poly HRP (horseradish peroxidase) conjugate to locate where the mouse or rabbit primary antibody is bound to the target antigen. The complex formed between Poly HRP conjugate and the mouse or rabbit primary antibody is observed through the use of a substratechromogen solution which, when added, results in a colored precipitate at the antigen location. The staining location and pattern is easily observable by light microscopy.

Genemed Power-Stain 1.0 Poly HRP DAB Kit for Mouse + Rabbit - Immunohistochemistry Reagents
Genemed® Power-Stain™ 1.0 Poly HRP DAB Kit for Mouse + Rabbit, 15 mL

Detection systems

Product code

Product name and quantity

52‐0006

Genemed® Power‐Stain™ 2.0 Poly HRP Kit for Mouse + Rabbit; 15 mL

54‐0006

Genemed® Power‐Stain™ 2.0 Poly HRP Kit for Mouse + Rabbit; 100 mL

52‐0017

Genemed® Power‐Stain™ 1.0 Poly HRP DAB Kit for Mouse + Rabbit; 15 mL

54‐0017

Genemed® Power‐Stain™ 1.0 Poly HRP DAB Kit for Mouse + Rabbit; 100 mL

52‐0020

Genemed® Power‐Stain™ 1.0 Poly AP for Mouse and Rabbit; 15 mL

52‐0022

Genemed® Power‐Stain™ 1.0 Poly HRP AEC Kit for Mouse + Rabbit; 15 mL

54‐0022

Genemed® Power‐Stain™ 1.0 Poly HRP AEC Kit for Mouse + Rabbit; 100 mL

52‐0023

Genemed® Power‐Stain™ 1.0 Double Stain (Poly HRP for Mouse + Poly AP for Rabbit);
15 mL


Regulatory status:  IVD, FDA class I


 

Buffers

Product code

Product name

Quantity

10-0044

Genemed® PBS Powder

2 packs

10-0029

Genemed® SSC Buffer (20X)

100 mL

10-0028

Genemed® TBST (Tris Buffered Saline and 0.05% Tween 20),
pH 7.4 (20X)

100 mL

Chromogens

Product code

Product name

Quantity

10-0005

Genemed® AEC Substrate

100 mL

10-0047

Genemed® AEC Substrate

15 mL

10-0048


Genemed® Sensitive DAB Substrate Kit

200 mL

Diluents

Product code

Product name

Quantity

10‐0058

Genemed® Antibody Diluent for Automated Stainers

500 mL

10‐0001

Genemed® Primary Antibody Diluent

500 mL

Counterstain & mounting

Product code

Product name

Quantity

10‐0034

Genemed® PBS Powder

15 mL

10‐0033

Genemed® SSC Buffer (20X)

15 mL

10‐0027

Genemed® TBST (Tris Buffered Saline and 0.05% Tween 20),
pH 7.4 (20X)

100 mL

10‐0041

Genemed® Mini PAP Pen

1 pen

10-0045


Genemed® Super PAP Pen

1 pen

Prestaining

Product code

Product name

Quantity

10-0039

Genemed® A/B Block Kit (Avidin/Biotin Blocking Solution)

15 mL

10-0032

Genemed® Blocking Solution (Non‐immune)

100 mL

10-0040

Genemed® C‐Block (Casein Blocking Solution)

100 mL

Pretreatment

Product code

Product name

Quantity

10-0020

Genemed® PBS Powder

2 packs

10-0022

Genemed® SSC Buffer (20X)

100 mL

10-0056

Genemed® TBST (Tris Buffered Saline and 0.05% Tween 20),
pH 7.4 (20X)

100 mL

10-0025

Genemed® Proteinase K

50 mL

10-0037

Genemed® Tris EDTA Buffer pH 9 (20X)

100 mL

10-0046 

Genemed® Tris EDTA Buffer pH 9

1 L, RTU

Regulatory status:  IVD, FDA class I

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