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Tissue-Tek Genie® Advanced Staining System

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An IHC & ISH stainer system that provides predictable turnaround time with maximum flexibility

The Tissue-Tek Genie® Advanced Staining System is the first and only fully automated, true random access stainer for immunohistochemistry (IHC) and in situ hybridization (ISH) that features 30 completely independent staining stations.  This IHC & ISH stainer system provides uncompromised fast and predictable turnaround time (TAT) for unprecedented staining quality of the entire antibody portfolio. 

With the Tissue-Tek Genie Advanced Staining System, you now have the capability to:  

  • Run any slide, any stain, any time, any instrument  
  • Eliminate batching of slides 
  • Run cases together on one instrument 
  • Run IHC tests within 2 – 3 hours for faster and predictable TAT 
  • Eliminate diluting reagents, all Ready-to-Use (RTU)
  • Eliminate the rail effect.  Full slide coverage

This superior performance is possible due to innovations Sakura Finetek brings to advanced staining:

  • 30 completely, independent staining stations with active heating/cooling and no slide scheduler 
  • True continuous random access 
  • Fully automated staining from dewaxing to counterstain with no alteration in TAT
  • Advanced capillary gap technology for whole slide coverage 
  • The first and only single-use capsule format for advanced staining applications to enable laboratories to run any test, any time, on any station
  • The first and only peristaltic dispense mechanism in advanced staining for precise volume delivery without any carryover or cleaning
  • Bulk reagents are all RTU, no requirement for refrigeration, mixing, or dilution 
  • Separation of hazardous from non-hazardous waste 

To increase quality and reproducibility of stains, Sakura Finetek established a new rigorous methodology to develop reagents and protocols for:

  • Stain quality that is scored optimal by several experts in pathology
  • Fast and predictable TAT, unprecedented by current solutions in the market
  • Innovation that enables continuous workflow with minimal disruption and simpler operation

The Tissue-Tek Genie Detection Kits (DAB, AP Red and DUO) along with our Tissue-Tek Genie RTU antibodies and ancillary reagents with evaluated protocols ensures users are provided consistent, quality staining results with reproducibility that laboratories have come to expect from Sakura Finetek IHC & ISH stainer products.  These staining results were independently evaluated by a leading quality assurance organization.
 

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IHC catalog
  • 30 completely independent and scheduler-free staining stations for IHC/ISH
    Predictable TAT with true random access for same-day diagnosis
  • Innovative, prefilled, RTU Capsules for single test for true random access
    Can perform a test, any time (whenever a station is idle), any station (idle station), any stain (no need to manage reagents on-board), and any instrument (no need to move antibodies between instruments)
  • Whole slide coverage
    • Ability to place controls and patient’s sections anywhere on a slide
    • Eliminate “rail” artifacts
    • Eliminate the need for tiles, coverlids, or oily reagents to limit evaporation
    • Eliminate the need to clean tiles, coverlids, or oily reagents on slides
  • Enhanced waste management
    • Separation of hazardous from non-hazardous waste
    • Low total volume waste generation
  • Unique advance gap technology
    Fast fill and drain of the slide staining chamber
  • Single slide loading and unloading
    LEAN, batch-free staining
  • Sakura Finetek developed and manufactured detection systems, antibodies, probes and reagents
    • Consistent reagent quality and performance
    • Sensitive and specific detection systems for mouse and rabbit antibodies

Product name

Tissue-Tek Genie® Advanced Staining System

Product code

8201

Applications

Automated immunohistochemistry (IHC) and in-situ hybridization (ISH)

Dimensions 
 

65.0 (W) x 29.6 (D) x 63.0 (H) inches
165.0 (W) x 75.0 (D) x 160.0 (H) cm

Weight

1,280 lbs (580 kg)

Power Requirements

115 VAC ± 10%, 50/60 Hz, single phase, 20 A

Turnaround time

1 hour 44 minutes to 2 hours 44 minutes IHC including dewaxing, antigen retrieval and counterstaining

Throughput

Up to 90 IHC slides in 8 hours

Temperature control of
reagent on slides

50°F to 208°F (10°C to 98°C)

Instrument capacity

30 Independent slide stations

Slide requirements
 

25 x 75 mm or 26 x 76 mm
positively charged slides

Modularity

Up to 5 Tissue-Tek Genie® Advanced Stainers can be controlled from one PC

Instrument operating
conditions
 

Temperature range: 59°F to 86°F (15°C to 30°C)
Relative humidity range: 30 – 80%, non-condensing

Antibody and probe
dispensing options


 

Prefilled RTU Capsules
Prefilled RTU Cartridges 
User-Fillable Capsules 
User-Fillable Cartridges 
Manual pipetting

ETL Certification   

ETL certification mark is labeled on the exterior panel

Safety requirements

UL 61010-1:2012 Ed.3+R:29Apr2016] 
CAN/CSA C22.2#61010-1:2012 Ed.3 +G1
UL 61010-2-101 Issued: 2015/08/14 Ed: 2

Standards

CSA C22.2#61010-2-101:2015 Ed.2] 
UL 61010-2-010:2015 Ed.3]
CSA C22.2#61010-2-010:2015 Ed.3]

Regulatory status

IVD, FDA class 1

Tissue-Tek Genie® Capsules

The innovative single-use Capsules make Genie the most convenient stainer on the market, eliminating batching and sorting of slides, and giving you the flexibility to load any slide, any stain, any time, any station on any Genie.

 A gloved hand places a component into a laboratory instrument with numbered slots and indicator lights.Benefit from using Capsules:

1. Run cases or single slides without the need to batch slides by antibody.
2. Save time loading slides whenever a staining station is available.
3. Use for any slide volume of any biomarkers.




The Capsule with an attached tag (used for identification) is inserted into a reusable plastic Reagent Dispensing Area (RDA) and the RDA is loaded onto any of the available 30 independent staining stations along with the slide.


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See how the Capsules are produced here:

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In summary, this innovative technology enables laboratories to quickly load slides and reagents for an IHC stain to gain continuous workflow with short and predictable TAT.
 

Gallery

Video gallery

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