NanoZoomer® S540 Digital slide scanner

Sophisticated simplicity in high-capacity digital slide scanning

The NanoZoomer® S540 is designed to transform high-volume slide digitization with a combination of fast scanning speeds,flexible slide rack compatibility, and intuitive operation. With support for standard slide format racks and continuous loading,the S540 helps laboratories efficiently convert large numbers of glass slides into high-quality digital images with minimal operator intervention.

Speed

The Nano Zoomer S540 delivers rapid whole slide scanning across both 20× and 40× modes, enabling efficient image capture inapproximately 30 seconds per slide (15×15 mm area). Its optimized scanning performance helps laboratories achieve high throughput, more than 82 slides per hour, without compromising image quality.

Capacity & Workflow

Built for demanding workflows, the S540 supports up to 540 standard slides when paired with 30-slide racks or 360 slides with20-slide Sakura basket. Continuous loading lets users insert and exchange racks during scanning, reducing downtime. An intuitive touchscreen interface simplifies scan control and monitoring directly at the instrument.

Image Quality & Integration

High-resolution optics, pre-focus mapping, and included Z-stack capability ensure detailed digital slide imagery. Integrated 1Dand 2D barcode reading supports slide traceability, while JPEG image compression balances image fidelity with manageable digital storage.


  • High-throughput scanning (up to 82slides/hour)
    Keeps pace with high-volume labs and reduces turnaround time
  • Maximum capacity up to 540 slides (30-slide racks x 18)
    Supports large batch scanning for streamlined operations
  • Continuous loading capacity
    Insert or exchange racks anytime without interrupting scanning
  • Fully-automatic and semi-automaticscanning modes
    Adapt scanning workflows to lab preferences and case requirements
  • Customizable scan profiles
    Standardize scan parameters and improve workflow consistency
  • Approx. 30 seconds per slide (20x /40x mode)
    Enables rapid digitization without compromising workflow efficiency
  • Compatibility with both 20-slideSakura baskets and 30-slide racks
    Flexible configuration to match lab volume and workflow needs
  • Rack priority setting
    Optimize urgent case handling directly from the scanner or software
  • AI tissue detection
    Ensures targeted scanning of tissue areas while avoiding blank regions
  • QC (Quality Check) mode
    Verify image quality before accepting whole slide image

Product name

NanoZoomer S540 Digital slide scanner

Product code

C17400-01

Application

High-throughput digital slide scanning with rack compatibility and continuous loading for whole slide image acquisition

Dimensions

29.5 (W) x 27.2 (D) x 52.4 (H) inches
75.0 (W) x 69.0 (D) x 133.1 (H) cm

Weight

Scanner: Approx. 125 kg

Dedicated cart: Approx. 65 kg

Power requirement

AC 100 V to AC 240 V

Approx. 200 VA (scanner only)

Capacity

Max. 540 slides (30 slides per 18 racks)

Max. 360 slides (20 slides per 18 Sakura baskets)

Scan speed

Approx. 30s/slide (20x / 40x mode)

Throughput

More than 82 slides/hour (20x / 40x mode)

Objective lens

20x N.A. 0.75; 20x / 40x options available

Scanning resolution

~0.46 μm/pixel (20x) / 0.23 μm/pixel (40x)

Focusing Method

Pre-Focus map

Z-stack feature

Included; Customizable up to 99 layers

Image compression

JPEG

Readable barcodes

1D Barcodes: Code 39, Code 128, Interleaved 2 of 5, Codabar, EAN-8, UPC-E

2D Barcodes: DataMatrix (ECC200), QR Code (QR Code Model-2)

Regulatory status

For Research Use Only. Not for use in diagnostic procedures.

Gallery

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