Regulatory status: IVD, FDA Class I
60-0015-7 7mL RTU
61-0015 1mL concentrate
This antibody labels the Chromogranin A protein in the cytoplasm of neuroendocrine cells in both normal and neoplastic tissue. Moderate to strong granular cytoplasmic staining of neuroendocrine cells within the epithelial surface is observed in gastrointestinal organs; granular cytoplasmic staining is also seen in axons and perikarya of neurons and ganglion cells in the submucosa, whereas epithelial cells and muscle cells are negative. This antibody may be useful in the identification of neuroendocrine tumors when used in a panel of antibodies.