Tissue-Tek Prisma® Plus Automated Slide Stainer

To support pathology laboratories to maintain CAP compliance you can scan the barcode of our first Tissue-Tek Prisma® H&E Stain Kit #1 and automatically log

Fast gets even Faster

Provide pathologists with your slides faster than ever.  The Tissue-Tek Prisma® Plus Automated Slide Stainer remains the highest throughput tissue stainer with up to 530 slides per hour while still producing consistent high quality slides, thanks to the new intelligent scheduler.  Enhanced features include barcode scanning and documentation, reagent grouping and Tissue-Tek® iSupport™ to provide remote diagnostics and quick issue resolve for your peace of mind.

To support pathology laboratories to maintain CAP compliance you can scan the barcode of our first Tissue-Tek Prisma® H&E Stain Kit #1 and automatically log the information of that kit and its components.  The Tissue-Tek Prisma Plus stores and documents the expiration date as well as the time reagents were loaded on the instrument so you can be alerted before expirations, providing another level of patient safety and documentation.

Our H&E stainer utilizes efficient robotics and intuitive software to run multiple protocols simultaneously as well as allowing to prioritize chosen runs with the STAT feature. With the Tissue-Tek Prisma Plus' flexible choice of 50 colors that can be assigned to reagents or stations, running H&E, PAP or Special Stains has never been easier.  Users can better visually differentiate the stain components and their location within the tissue stainer.  Various stains running at the same time are easily customizable with your choice from 50 user-defined staining protocols, meeting the demands of any pathologist.
Connect the Tissue-Tek Prisma Plus with your choice of  the Tissue-Tek Film® Coverslipper or the Tissue-Tek® Glas™ g2 Coverslipper a truly integrated, fully automated walkaway staining process from slide baking to slide drying. Your laboratory can now further increase productivity, especially appreciated during daily peak demand hours, further reducing user stress levels by forwarding high quality stained and coverslipped slides to the pathologists faster.

Read further about how pairing the Prisma® Plus with the Film® Coverslipper reduced scanning errors dramatically on over 800,000 slides!



Barcode reader
  • Keeps track of reagent usage and alerts user before their expiration
Tissue-Tek® iSupport 
  • Helps resolve issues quicker and remotely
  • Prioritizes runs over standard workload
Precise operations
  • Standardizes staining with full control by user
Standard and Expanded configurations
  • Allows for customization of multiple protocols (H&E, PAP, Special Stains, dewaxing, rehydration, dehydration, etc.)
Continuous loading
  • Decreases turn around time (TAT)
Capacity for parallel runs
  • Run H&E, specials, dewaxing, rehydration, dehydration at the same time
Splitting of reagents and grouping of reagent stations
  • Doubles the number of slides until a reagent needs replacement
2 drying stations
  • Slimplifies the workflow reducing number of steps
50 color choice for reagents
  • Eases the identification of reagents, especially appreciated in parallel runs with reagents that cannot be shared between the stain protocols
Activated carbon filters and venting kit
  • Improves the safety of lab personnel
Connectivity to coverslipper
  • Creates an integrated, fully automated walkaway staining process from slide baking to slide drying
52+ weeks mean time between repairs
  • Reduces stress caused by downtime
Product name Tissue-Tek Prisma® Plus Standard Configuration
Tissue-Tek Prisma® Plus Special Staining Configuration
Product code 6170
Application Automated preparation of routine histological and cytological stains for use in pathology laboratories to assist with the following tasks: staining, dewaxing, rehydration, dehydration, etc.
Throughput Up to 530 slides per hour


49.2 (W) X 28.0 (D) X 25.0 (H) inches
125 (W) X 71 (D) X 63 (H) cm
Weight 330 lbs (150 kg)

Number of reservoirs

Start - 1 to 3 stations
Reagent - 31 to 51 reservoirs
Drying - 0 to 2 stations
Wash - 0 to 4 stations (8 programmable steps)
Heating (optional) - 2 stations


Reagent volume - 160, 260 and 680 mL
Staining protocols - 11 runs continuously loading, and simultaneously running
Baskets - 10 or 20 slide basket
Loading - up to 60 slides per run


Drying station - 86 ~ 149°F (30 ~ 65°C)
Heating station - 86 ~ 158°F (30 ~ 70°C)
Heating 2 stations
Staining Up to 50 protocols
Security Door and cover
Certifications IEC 61010-1 2nd ed., CAN/CSA C22.2 61010-1, UL 61010-1
Regulatory status IVD, FDA Class I

Product code

Product name and quantity

4768 Tissue-Tek® 20-Slide Basket; 10/case
6136 Tissue-Tek Prisma® 20-Slide Basket Adapter
6147 Tissue-Tek Prisma® Standard Solution Reservoir, 680 mL
6151 Tissue-Tek Prisma® Standard Solution Reservoir Lid
6145 Tissue-Tek Prisma® Small Solution Reservoir, 260 mL
6146 Tissue-Tek Prisma® Small Solution Reservoir Lid
6134 Tissue-Tek Prisma® Link System for Tissue-Tek Film® Coverslipper
6168 Tissue-Tek Prisma® Link System for Tissue-Tek® GlasTM g2 Coverslipper
6161 Tissue-Tek Prisma® Station Labels, START, END, PE
6162 Tissue-Tek Prisma® Basket Adapter Label
6160 Tissue-Tek Prisma® Activated Carbon Filter; 2/case
6179 Tissue-Tek Prisma® Plus Barcode Reader

MWEB0201 Rev.H

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