Tissue-Tek Prisma® Plus

Fast gets even Faster

The new Tissue-Tek Prisma® Plus remains as the highest throughput stainer with up to 530 slides per hour while still producing consistent high quality slides.  Enhanced features include barcode scanning and documentation, reagent grouping and Sakura’s Tissue-Tek® iSupport™ program provides remote diagnostics and peace of mind.

To help with CAP compliance, users can now scan the barcode of the newly introduced Prisma H&E Stain Kit and automatically log the information of that kit and its components.  The Tissue-Tek Prisma® Plus stores and documents the expiration date and time reagents were loaded on the instrument.

The Tissue-Tek Prisma® Plus utilizes efficient robotics and intuitive software to run multiple protocols simultaneously. With the Tissue-Tek Prisma® Plus’ flexible choice of 50 stain component color assignment, running H&E, PAP or special stains has never been easier.  Users can better visually differentiate the stain components and their location within the stainer.  Various stains running in parallel are easily customizable with the choice of 50 user defined staining protocols, meeting the demands of any pathologist.
Connecting the Tissue-Tek Prisma® Plus with the Tissue-Tek Film® Coverslipper or Tissue-Tek® Glas™ g2 Coverslipper creates an integrated, fully automated walkaway staining process from slide baking to slide drying. Laboratories can now further increase productivity, especially appreciated during daily peak demand hours, further reducing user stress levels by forwarding high quality stained and coverslipped slides to the pathologists faster.



Barcode reader
  • Keep track of reagent usage and alert user before expired reagents
  • Help resolve issues quicker
  • Prioritize run over standard workload
Precise programming
  • Standardizes staining with full control by user
Standard and Expanded configurations
  • Allows for customization of multiple protocols (H&E, Pap, Special Stains, etc.)
Activated carbon filters and venting kit
  • Improves lab staff safety
Tissue-Tek Prisma® Plus Slide Stainer


Up to 530 slides per hour


49.2 x 28 x 25 inches (125 x 71 x 63 cm)


330 lbs (150 kg)

Number of Reservoirs

Start - 1 to 3 stations
Reagent - 31 to 51 reservoirs
Drying - 0 to 2 stations
Wash - 0 to 4 stations (8 programmable steps)
Heating (optional) - 2 stations


Reagent volume - 160, 260 and 680 mL
Staining protocols - 11 runs continuously loading, and simultaneously running
Baskets - 10- or 20- slide basket
Loading - Up to 60 slides per run


Drying station - 86 ~ 149°F (30 ~ 65°C)
Heating station - 86 ~ 158°F (30 ~ 70°C)
Certifications IEC 61010-1 2nd ed., CAN/CSA C22.2 61010-1, UL 61010-1

Glas g2 Coverslipper


Up to 360 slides per hour


29.5 x 24.4 x 29.5 inches (75 x 62 x 75 cm)


242 lbs (110 kg)


Loading- Up to 60 slides
Unloading - Up to 240 slides
Film Coverslipper


Up to 1,080 slides per hour


28.3 x 23 x 27.2 inches (72 x 58 x 69 cm)


165 lbs (75 kg)


Loading- Up to 60 slides
Unloading - Up to 240 slides
Optional - Slide Barcode Reading

Product code

Product name and quantity

4768 Tissue-Tek® 20-Slide Basket; 10/cs
6136 Tissue-Tek Prisma® 20-Slide Basket Adapter
6147 Tissue-Tek Prisma® Standard Solution Reservoir, 680 mL
6151 Tissue-Tek Prisma® Standard Solution Reservoir Lid
6145 Tissue-Tek Prisma® Small Solution Reservoir, 260 mL
6146 Tissue-Tek Prisma® Small Solution Reservoir Lid
6134 Tissue-Tek Prisma® Link System for Tissue-Tek Film® Coverslipper
6168 Tissue-Tek Prisma® Link System for Tissue-Tek GlasTM g2 Coverslipper
6161 Tissue-Tek Prisma® Station Labels, START, END, PE
6162 Tissue-Tek Prisma® Basket Adapter Label
6160 Tissue-Tek Prisma® Activated Carbon Filter; 2/case

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