Tissue-Tek AutoSection® Automated Microtome

Tissue-Tek AutoSection® delivers the next level in precision sectioning.Tissue-Tek AutoSection provides one-touch trimming and programmable sectioning with a host of built-in safety feat

A fully automated SMART microtome

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Tissue-Tek AutoSection® delivers the next level in precision sectioning.

Tissue-Tek AutoSection provides one-touch trimming and programmable sectioning with a host of built-in safety features. AutoSection automatically orients the block to the blade edge, using patented sensing and automated 3D specimen holder technology for precise XYZ orientation. It standardizes block orientation - even if the block was trimmed or sectioned on a different microtome - saving valuable tissue and technician time. With AutoTrim™, the AutoSection trims blocks automatically in just seconds with one-touch operation. This tissue-preserving feature is optimized for Tissue-Tek® Paraform® Sectionable Cassette System, although it also accommodates most common cassettes.

Multiple exclusive built-in safeguards make the Tissue-Tek AutoSection the leader in automated microtome user safety. One-touch trimming and sectioning eliminate repetitive hand wheel motions and reduce the risk of musculoskeletal disorders, while the sliding dispenser feature of Accu-Edge® blades eliminates direct handling of blades.

Compared to manual and motorized microtomes the SMART AutoSection showed the highest precision in section thickness using IHC staining and digital imaging technology.*  Read more about Robotic and Semi-Automated Microtomy Can Decrease Variability in Her2 Staining Intensity.  Programmable sectioning, it enables laboratories to implement standardized protocols for specific tissue or block types. 

* Poster USCAP 2017- Robotic and semi-automated microtomy can decrease variability in HER2 staining intensity.



AutoAlign™ function
  • Saves time and tissue with block to blade auto alignment
AutoTrim™ function
  • Saves time by facing blocks in 15 seconds or less
AutoSection function
  • Enables microtomy at the touch of a button  
  • Reduces Repetitive Motion Disorder in the lab
3D Chuck and Sensing Plate
  • Optimizes block alignment to preserve tissue during sectioning
Programmable sectioning
  • Standardizes sectioning throughout the lab
Wireless hand held remote control
  • Enables operation from either side of the instrument
Product names Tissue-Tek AutoSection® Automated Microtome
Product codes 5010
Application Sectioning of paraffin-embedded specimens for routine and research histology
Dimensions 16.5 (W) x 26.4 (D) x 17.4 (H) inches
42 (W) x 67 (D) x 44 (H) cm
Weight (with microtome) 121 lbs (55 kg)
Administrator access Password protected
Section thickness 0.5 - 100 microns
Trimming thickness 1 - 200 microns
Retraction distance No retraction, 20-100 microns
Sectioning speed 10 - 450 mm/second
Trimming speed 10 - 450 mm/second
Return speed 10 - 450 mm/second
Typical vertical stroke 5.2 inches (132 mm)
Typical horizontal stroke 0.37 inches (9.4 mm)
Number of presets Up to 15 different presets
Number of program steps Up to 16 steps
Number of user preferences Up to 32 different preferences
3D Chuck/Specimen Holder Vertical and horizontal axes adjustment range ± 4°
3D Chuck/Specimen Holder angle resolution 0.05°
Blade angle Fixed
Alignment to the blade edge ±0.05°
Alignment distance to the blade +/-10 microns
User interface display 4.3” color LCD touchscreen with 480 x 272 pixels
Remote Bluetooth® wireless remote
Date interface USB 2.0
Certifications UL 61010-1, CAN/CSA C22.2 #61010-1, CAN/CSA C22.2 #61010-2-101, IEC 61010-1:2001, IEC61010-2-101, EMC
Regulatory status IVD, FDA Class I

MWEB0173 Rev.G

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