Regulatory status: IVD, FDA Class I
60-0018-7 7mL RTU
61-0018 1mL concentrate
This antibody labels the cytokeratin 20 (CK20) protein in the cytoplasm of mature enterocytes and goblet cells of the gastric and intestinal mucosa in both normal and neoplastic tissue. Most colon adenocarcinomas, mucinous ovarian tumors, transitional cell and Merkel-cell carcinomas, gastric adenocarcinomas, bile system, and pancreas are CK20 positive. Most squamous cell carcinomas and adenocarcinomas from breast, endometrium, lung, and prostate may be CK20 negative, as well as non-mucinous tumors of the ovary and small-cell lung carcinomas. May be a useful tool when used in a panel of other antibodies.