Tissue-Tek Genie®
anti-CD21

Clone: EP64
Host clonality: rabbit monoclonal
Control tissue: tonsil, lymph node
Staining pattern: membraneous
Regulatory status: IVD, FDA Class I
Product code: 8260-C010: RTU, 10 capsules; 1 pack
8260-M250: RTU, 250 tests, 1 cartridge; 1 unit

 

CD21 is a membrane protein that serves as the receptor for complement component C3 (C3d) and the Epstein-Barr Virus (EBV). CD21 is expressed on dendritic cells and mature B-cells.
Tissue-Tek Genie<sup>&reg;</sup><br /> anti-CD21 Moderate membraneous expression of CD21 is present on the neoplastic lymphocytes in this chronic lymphocytic lymphoma (CLL/SLL), and the benign follicular dendritic cells show strong membraneous expression.

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Follicular dendritic cells within reactive follicles in this tonsil show strong membraneous staining for CD21. There is weak to moderate staining among the B-cells of the mantle zone.
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