Clone: GR013
Host clonality: rabbit monoclonal
Control tissue: tonsil or known CD23 positive B-cell lymphoma
Staining pattern: membraneous and some cytoplasmic
Regulatory status: IVD, FDA Class I
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Product code:
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8262-C010: RTU, 10 capsules; 1 pack
8262-M250: RTU, 1 cartridge, 250 tests; 1 unit
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CD23 is type II membrane glycoprotein and is primary expressed on the surface of a sub-population of B-cells in germinal center (mantle zone, and follicular dendritic cells). In tonsil, membrane staining is observed with follicular dendritic cells in germinal centers and activated B-cells in the mantle zones around germinal centers.
Moderate staining in B-chronic lymphatic leukemia.
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Moderate staining of activated B-cells in the mantle zone and follicular dendritic cells of germinal centers in tonsils.
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Negative staining of mantle cell lymphoma.