lymph node, tonsil, appendix
membraneous and cytoplasmic
Regulatory status: IVD, FDA Class I
8279-C010: RTU, 10 capsules; 1 pack
8279-M250: RTU, 250 tests, 1 cartridge; 1 unit
CD43 is membrane glycoprotein expressed on the surface of thymocytes, T-cells, and cells of the myeloid lineage. The antibody labels CD43 in normal and neoplastic cells.
No CD43 expression is seen in the germinal center or mantle zone B-cells of this benign lymph node. Strong membrane staining is demonstrated among the T-cells.
Strong membrane staining for CD43 is demonstrated in this small cell lymphoma/chronic lymphocytic leukemia (CLL/SLL).
Weak to moderate membrane staining for CD43 is seen in this plasmacytoma of bone.