Tissue-Tek Genie®

Clone: NK1
Host clonality: mouse monoclonal
Control tissue: lymph node and tonsil
Staining pattern: membraneous
Regulatory status: IVD, FDA Class I
Product code: 8338-C010: RTU, 10 capsules; 1 pack
8338-M250: RTU, 250 tests, 1 cartridge; 1 unit


CD57 is expressed on subtypes of T-cells, natural killer (NK) cells, and other peripheral blood mononuclear cells. CD57 is also present in glial cells, a variety of other neural and epithelial cells, as well as various neural tumors. In addition, CD57 is expressed in prostate tissue, prostate adenocarcinoma, papillary thyroid carcinomas and thymomas.
Tissue-Tek Genie<sup>&reg;</sup><br /> anti-CD57 CD57 is highly expressed in neural tissues and a strong membraneous expression pattern is seen among neurons and glial elements in this normal cerebrum.

A moderate to strong membraneous staining reaction for CD57 is seen among NK cells and a subset of CD8+ T-cells, as shown in the germinal center of this tonsil.

The cortical cells of this adrenal gland show a negative staining reaction for CD57, while the medullary cells show intense membraneous reactivity.
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