Tissue-Tek Genie®

Clone: EP211
Host clonality: rabbit monoclonal
Control tissue: pancreas, skin, prostate, melanoma
Staining pattern: cytoplasmic (with occasional dot-like pattern) and membraneous
Regulatory status: IVD, FDA Class I
Product code: 8283-C010: RTU, 10 capsules; 1 pack
8283-M250: RTU, 250 tests, 1 cartridge; 1 unit


CD63 is a 53 kD lysosomal membrane protein expressed by a broad range of tissues/cell types, including platelets, granulocytes, basophils, a subset of T-cells, endothelial cells, sweat gland, islets of Langerhans, pancreas, prostate, and melanoma.
Tissue-Tek Genie<sup>&reg;</sup><br /> anti-CD63 Strong cytoplasmic staining for CD63 is present among the metastatic melanoma cells involving a lymph node. There is no reactivity among the lymphocytes.

Trophoblasts and villus mesenchymal cells are negative for CD63.

Variable degrees of granular cytoplasmic reactivity for CD63 are seen in the cortical regions of the adrenal gland.
Back to top