Tissue-Tek Genie®

Clone: EP232
Host clonality: rabbit monoclonal
Control tissue: tonsil, appendix liver, placenta, bone marrow, AML-M6
Staining pattern: membraneous and cytoplasmic
Regulatory status: IVD, FDA Class I
Product code: 8322-C010: RTU, 10 capsules; 1 pack
8322-M250: RTU, 250 tests, 1 cartridge; 1 unit


CD71 is regarded as a proliferation marker, and is expressed on myelocytes, activated B- and T-cells, thymocytes, macrophages, proliferating cells, as well as metabolically active cells, e.g., placental syncytiotrophoblasts, basal keratinocyte, hepatocyte, endocrine cells, and spermatocytes. CD71 expression is observed in various neoplasms.
Tissue-Tek Genie<sup>&reg;</sup><br /> anti-CD71 Strong membraneous and cytoplasmic staining is seen among the erythroblasts and erythroid precursors in this bone marrow involved by AML-M6.

Moderate cytoplasmic reactivity for CD71 is seen among the spermatocytes and Leydig cells of this testis.

The acini and ductal epithelial cells of pancreas show a weak to negative cytoplasmic or membraneous reactivity pattern for CD71.
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