tonsil, esophagus, prostate, and squamous cell carcinoma
Regulatory status: IVD, FDA Class I
8300-C010: RTU, 10 capsules; 1 pack
8300-M250: RTU, 250 tests, 1 cartridge; 1 unit
Cytokeratin 14 (CK14) is a member of the cytokeratin family that is usually found as a heterodimer with cytokeratin 5 to form the cytoskeleton of epithelial cells. CK14 is expressed in the basal cells of squamous epithelia, myoepithelial cells, and mesothelial cells.
Strong cytoplasmic expression of CK14 is demonstrated among the basal cells of the prostate.
No CK14 expression is observed in breast adenocarcinoma.