Tissue-Tek Genie®
anti-Cytokeratin Antibody Cocktail [AE1/AE3]

Clone: AE1/AE3
Host clonality: mouse monoclonal
Control tissue: normal liver, esophagus, lung
Staining pattern: cytoplasmic
Regulatory status: IVD, FDA Class I
Product code: 8307-C010: RTU, 10 capsules; 1 pack
8307-M250: RTU, 250 tests, 1 cartridge; 1 unit


Cytokeratins are a group of intermediate filament proteins expressed in cells of epithelial origin. The antibody cocktail of clones AE1 and AE3 labels both acidic and basic cytokeratins in normal and neoplastic cells.
Tissue-Tek Genie<sup>&reg;</sup><br /> anti-Cytokeratin Antibody Cocktail [AE1/AE3] The AE1/AE3 cocktail shows strong cytoplasmic and membraneous staining in this high-grade neuroendocrine carcinoma of lung. Patchy golgi (dot-like) staining is also observed.

The antibody cocktail, AE1/AE3, shows moderate cytoplasmic and membraneous reactivity in the hepatocytes of normal liver, with strong cytoplasmic staining of bile ducts.
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