Clone: polyclonal
Host clonality: rabbit polyclonal
Control tissue: tonsil, appendix
Staining pattern: cytoplasmic
Regulatory status: IVD, FDA Class I
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Product code:
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8333-C010: RTU, 10 capsules; 1 pack
8333-M250: RTU, 250 tests, 1 cartridge; 1 unit
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Lysozyme is a ubiquitous enzyme found in tears, saliva, human milk, mucus, gastrointestinal secretions, urine, serum, spleen, lung, and kidney. Lysozyme immunoreactivity is found in cytoplasmic granules of the macrophages, the granulocytes (polymorphonuclear neutrophils), reactive histiocytes, myeloid cells, and some epithelial cells.
A diffuse moderate to strong granular cytoplasmic staining reaction for lysozyme is present in this acute myeloid leukemia (AML).
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Gastric epithelium shows a range of moderate to strong cytoplasmic reactivity for lysozyme among epithelial cells.
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The appendiceal mucosa shows a weak to moderate cytoplasmic staining reaction for lysozyme among macrophages, neutrophils, histiocytes, and monocytes. No staining of the appendiceal epithelium is observed.