Tissue-Tek Genie®

Clone: EP49
Host clonality: rabbit monoclonal
Control tissue: colon, appendix, tonsil
Staining pattern: nuclear
Regulatory status: IVD, FDA Class I
Product code: 8326-C010: RTU, 10 capsules; 1 pack
8326-M250: RTU, 1 cartridge, 250 tests; 1 unit


MSH6 is expressed in normal proliferating cells and, when heterodimerized with MSH2 (MutS homolog 2), is involved in repairing DNA mutations which may occur during DNA replication.
Tissue-Tek Genie<sup>&reg; </sup><br /> anti-MSH6 Strong staining in normal appendix.

Strong staining in colon adenocarcinoma.

Negative staining of colon adenocarcinoma cells with loss of MSH6 expression.
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