mammaglobin positive normal breast, breast carcinoma, skin
Regulatory status: IVD, FDA Class I
8240-C010: RTU, 10 capsules; 1 pack
8240-M250: RTU, 250 tests, 1 cartridge; 1 unit
Low level of expression of mammaglobin is seen in normal breast. Its expression is markedly increased in breast carcinoma and is directly correlated with a higher grade. Mammaglobin is positive in about 80% of breast carcinomas, and is more frequently expressed than GCDFP-15.
Moderate to strong cytoplasmic reactivity for mammaglobin is seen in this invasive breast carcinoma.
The epithelial cells of this invasive ductal carcinoma of breast, as well as the benign duct in the background, show predominantly weak to moderate membraneous reactivity for mammaglobin.
Ducts and glomerular cells of the kidney show no reactivity for mammaglobin.