Clone: HMB45/EP43/T311
Host clonality: mouse and rabbit monoclonal
Control tissue: skin, melanoma, adrenal gland
Staining pattern: cytoplasmic
Regulatory status: IVD, FDA Class I
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Product code:
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8371-C010: RTU, 10 capsules; 1 pack
8371-M250: RTU, 250 tests, 1 cartridge; 1 unit
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PMEL17, MART-1 and tyrosinase are proteins expressed in normal melanocytes, and are often detected in melanomas.
![Tissue-Tek Genie<sup>®</sup><br /> anti-Melanoma Pan Antibody Cocktail [HMB45/EP43/T311]](/getattachment/d5a6a698-8001-45dd-81bb-6b03aebf5fc9/File-Name "Tissue-Tek Genie<sup>®</sup><br /> anti-Melanoma Pan Antibody Cocktail [HMB45/EP43/T311]")
The pan-melanoma antibody cocktail demonstrates strong cytoplasmic reactivity among intra-epithelial melanocytes and the cells of this blue nevus. No staining is seen within the squamous epithelium, stromal fibroblasts or endothelial cells. (Alkaline Phosphatase Red detection).
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Weak to moderate cytoplasmic staining is seen in the adrenal gland. (Alkaline Phosphatase Red detection).