mouse and rabbit monoclonal
skin, melanoma, adrenal gland
Regulatory status: IVD, FDA Class I
8371-C010: RTU, 10 capsules; 1 pack
8371-M250: RTU, 250 tests, 1 cartridge; 1 unit
PMEL17, MART-1 and tyrosinase are proteins expressed in normal melanocytes, and are often detected in melanomas.
The pan-melanoma antibody cocktail demonstrates strong cytoplasmic reactivity among intra-epithelial melanocytes and the cells of this blue nevus. No staining is seen within the squamous epithelium, stromal fibroblasts or endothelial cells. (Alkaline Phosphatase Red detection).
Weak to moderate cytoplasmic staining is seen in the adrenal gland. (Alkaline Phosphatase Red detection).