lung, kidney, and known napsin A positive lung adenocarcinoma
Regulatory status: IVD, FDA Class I
8331-C010: RTU, 10 capsules; 1 pack
8331-M250: RTU, 250 tests, 1 cartridge; 1 unit
Napsin A is a protease that is predominantly expressed in the lung and kidney. Napsin A is expressed in alveolar type II pneumocytes in lung and proximal tubules in kidney.
Cells of this lung adenocarcinoma show strong cytoplasmic expression of Napsin A. Lung squamous carcinomas and mesotheliomas are negative for Napsin A.
Cells of the proximal tubules in normal kidney show moderate to strong granular cytoplasmic staining for Napsin A.
Colonic epithelium shows no expression of Napsin A.