Tissue-Tek Genie®
anti-Neuron Specific Enolase

Clone: EP319
Host clonality: rabbit monoclonal
Control tissue: appendix, colon, pancreas, and tumors derived from neuron and endocrine
Staining pattern: cytoplasmic and nuclear
Regulatory status: IVD, FDA Class I
Product code: 8447-C010: RTU, 10 capsules; 1 pack
8447-M250: RTU, 250 tests, 1 cartridge; 1 unit


Neuron-specific enolase (NSE) is a gamma subunit homodimer and is the dominant form of the enolase isoenzymes found in neuronal and neuroendocrine cells.
Tissue-Tek Genie<sup>&reg;</sup><br /> anti-Neuron&nbsp;Specific Enolase Strong cytoplasmic staining for NSE is seen in this neuroendocrine carcinoma (Merkel cell caracinoma).

Pancreatic acinar cells and ductal epithelium are negative for NSE expression, while islet cells are positive.
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