Tissue-Tek Genie®
anti-Neuron Specific Enolase

Clone: EP319
Host clonality: rabbit monoclonal
Control tissue: appendix, colon, pancreas, and tumors derived from neuron and endocrine
Staining pattern: cytoplasmic and nuclear
Regulatory status: IVD, FDA Class I
Product code: 8447-C010: RTU, 10 capsules; 1 pack
8447-M250: RTU, 250 tests, 1 cartridge; 1 unit

 

Neuron-specific enolase (NSE) is a gamma subunit homodimer and is the dominant form of the enolase isoenzymes found in neuronal and neuroendocrine cells.
Tissue-Tek Genie<sup>&reg;</sup><br /> anti-Neuron&nbsp;Specific Enolase Strong cytoplasmic staining for NSE is seen in this neuroendocrine carcinoma (Merkel cell caracinoma).

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Pancreatic acinar cells and ductal epithelium are negative for NSE expression, while islet cells are positive.
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