A strong nuclear staining reaction is observed among the neoplastic cells of this diffuse large B-cell lymphoma.
There is a strong nuclear staining reaction for OCT.2 among the germinal center B-cells and a weak to moderate staining among the cells of the mantle zone.
The Reed-Sternberg and Hodgkin cells of this classic Hodgkin lymphoma show a negative staining reaction for OCT.2, while background B-cells and plasma cells show moderate to strong nuclear reactivity.