membraneous and cytoplasmic
Regulatory status: IVD, FDA Class I
8235-C010: RTU, 10 capsules; 1 pack
8235-M250: RTU, 250 tests, 1 cartridge; 1 unit
PLAP is a membrane-bound glycosylated dimeric enzyme expressed primarily in the placenta, and also in the endocervix and fallopian tubes. It is closely related to the intestinal form of the enzyme as well as to the placental-like form.
Strong diffuse cytoplasmic and membrane staining is seen in this seminoma and within the tubules showing intratubular germ cell neoplasia.
.No expression of PLAP is seen in the epithelial cells or in lymphoid follicles of the appendix.