Tissue-Tek Genie® Advanced Staining System

Predictable turnaround time with maximum flexibility

Introducing the Tissue-Tek Genie® Advanced Staining System: the first and only fully automated, true random access stainer for immunohistochemistry (IHC) and in situ hybridization (ISH) that features 30 completely independent slide stations.  This system provides uncompromised fast and predictable turnaround time (TAT) for unprecedented staining quality.

With the Tissue-Tek Genie Advanced Staining System, you now have the capability to:  
  • Run any slide, any time, any station, any antibody 
  • Eliminate batching of antibody tests 
  • Run cases together on one instrument 
  • Run IHC tests within 2 - 3 hours for faster and predictable TAT 
  • Eliminate diluting any reagent to ready-to-use (RTU) 
  • Eliminate the rail effect.  Capable of staining tissue sections that cover the entire slide 
  • Increase personnel safety while reducing costs 
This superior performance is possible due to innovations Sakura Finetek brings to advanced staining:
  • 30 completely, independent slide stations with active heating/cooling and no slide scheduler 
  • True continuous random access 
  • Fully automated staining from dewaxing to counterstain with no alteration in TAT
  • Advanced capillary gap technology for whole slide coverage 
  • The first and only single-use capsule format for advanced staining applications to enable laboratories to run any test, any time, on any station
  • The first and only peristaltic dispense mechanism in advanced staining for precise volume delivery without any carryover or cleaning
  • Bulk reagents are all RTU, no requirement for refrigeration, mixing, or dilution 
  • Separation of hazardous from non-hazardous waste 
To increase quality and reproducibility of stains, Sakura Finetek established a new rigorous methodology to develop reagents and protocols for:
  • Stain quality that is scored optimal by several experts in pathology
  • Fast and predictable TAT, unprecedented by current solutions in the market
  • Innovation that enables continuous workflow with minimal disruption and simpler operation
The Tissue-Tek Genie® Pro Detection Kit, DAB with Tissue-Tek Genie RTU antibodies and ancillary reagents with evaluated protocols ensures users are provided consistent, quality staining results with reproducibility that laboratories have come to expect from Sakura Finetek products.These staining results were independently evaluated by a leading quality assurance organization.



30 Completely independent and scheduler-free slide stations for IHC/ISH
  • Predictable TAT with true random access for same-day diagnosis                                              
Unique Advanced Gap Technology
  • Whole slide coverage
  • Fast fill and drain of the Slide Staining Chamber
Exclusive, prefilled, RTU Capsules for single test with true random access
  • Can perform a test, any time (whenever a station is idle), anywhere (idle station), and any antibody (no need to manage reagents on-board)
Single slide loading and unloading
  • LEAN, batch-free staining
Whole slide coverage

  • Ability to place controls and patient's sections anywhere on a slide
  • Eliminate "rail" artifacts
  • Eliminate the need for tiles, coverlids, or oily reagents to limit evaporation
  • Eliminate the need to clean tiles, coverlids, or oily reagents on slides
Sakura Finetek developed and manufactured detection system, antibodies, probes and reagents
  • Consistent reagent quality and performance
  • A single sensitive and specific detection system for mouse and rabbit antibodies
Enhanced waste management

  • Separation of hazardous from non-hazardous waste
  • Low total volume waste generation
Product name Tissue-Tek Genie® Advanced Staining System
Product code 8201
Dimensions (WxDxH)
65 x 30 x 63 inches
(165 x 75 x 160 cm)
Weight 1,280 lbs (580 kg)
Power Requirements 115 VAC ± 10%, 50/60 Hz, Single phase, 20 A

Automated IHC and ISH
Dewaxing, Antigen Retrieval, Rehydration, Digestion, Denaturation, Hybridization, Stringent Wash, Staining, Counterstaining
Turnaround time

1 Hour 44 minutes to 2 hours 44 minutes IHC including dewaxing, antigen retrieval and counterstaining
Throughput Up to 90 IHC Slides in 8 hours
Temperature control of
reagent on slides
50°F to 208°F (10°C to 98°C)
Instrument capacity 30 Independent Slide Stations
Slide requirements
25 x 75 mm or 26 x 76 mm
Positively Charged Slides
Modularity Up to 5 Tissue-Tek Genie® Advanced Stainers can be controlled from one PC
Instrument operating

Temperature Range: 59°F to 86°F (15°C to 30°C)
Relative Humidity Range: 30 - 80% R.H., Non-Condensing
Antibody and probe
dispensing options

Prefilled RTU Capsules
Prefilled RTU Cartridges 
User-Fillable Capsules 
User-Fillable Cartridges 
Manual Pipetting
Regulatory USA FDA class 1
ETL Certification    ETL certification mark is labeled on the exterior panel
Safety requirements UL 61010-1:2012 Ed.3+R:29Apr2016] 
CAN/CSA C22.2#61010-1:2012 Ed.3 +G1
UL 61010-2-101 Issued: 2015/08/14 Ed: 2
Standards CSA C22.2#61010-2-101:2015 Ed.2] 
UL 61010-2-010:2015 Ed.3]
CSA C22.2#61010-2-010:2015 Ed.3]


Product code

Product name and quantity

8865-G004 Tissue-Tek Genie® Dewax Solution, 4 bottles/case 
8742-G004 Tissue-Tek Genie® Citrate Antigen Retrieval Solution, 4 bottles/case
8744-G004 Tissue-Tek Genie® High pH Antigen Retrieval Solution, 4 bottles/case
8874-G004 Tissue-Tek Genie® Wash Buffer, 4 bottles/case
8826-K250 Tissue-Tek Genie® Pro Detection Kit, DAB, 250 tests/cartridge
8830-M250 Tissue-Tek Genie® Hematoxylin, 250 tests/cartridgee
8867-G004 Tissue-Tek Genie® Antibody Diluent, 4 bottles/case
8865-G001 Tissue-Tek Genie® Dewax Solution, 1 bottle  
8742-G001 Tissue-Tek Genie® Citrate Antigen Retrieval Solution, 1 bottle  
8744-G001 Tissue-Tek Genie® High pH Antigen Retrieval Solution, 1 bottle  


Product code

Product name and quantity

8217-G004 Tissue-Tek Genie® Waste Bottles, 4 bottles/case
8616-G090 Tissue-Tek Genie® Reagent Dispense Area (RDA), 90/box
8618-G090 Tissue-Tek Genie® Reagent Dispense Area Tag (RDA-Tag), 90/box
8637-K001 Tissue-Tek Genie® RDA-Tag Label Kit, 1 ribbon and 2 rolls for 
2,400 RDA-tag labels
8636-K001 Tissue-Tek Genie® Slide Label Kit, 1 ribbon and 3 rolls for 3,000 
slide labels
8622-G006 Tissue-Tek Genie® Antibody Cartridge, User-Fillable,
6 cartridges/box
8624-G006 Tissue-Tek Genie® Enzyme Cartridge, User-Fillable, 6 cartridges/box
8610-K050 Tissue-Tek Genie® User-Fillable Capsule Sealing System
8615-G001 Tissue-Tek Genie® User-Fillable Capsule Sealer
8611-G002 Tissue-Tek Genie® User-Fillable Capsule Tray
8617-G050 Tissue-Tek Genie® User-Fillable Capsules, 150/pack
8613-G050 Tissue-Tek Genie® User-Fillable Capsule Seals, 50/pack
9036 Tissue-Tek® SmartWrite® White Frosted Slide Charged, 10x100/case

Antibody Menu:

available upon request

MWEB0136 Rev.A