Disruption/Why are my tissue sections damaged?

Disruption: microscopic damage to the tissue within the section



Rough grossing

  • Change trimming and/or scalpel blades more frequently to prevent damage

Poor tissue processing

  • Soak block on ice bath to soften overprocessed, hard tissue; reprocess appropriately if under processed

Rough handling in water bath to dislodge wrinkles

  • Approach sections more gently with forceps or needles

Floating in water bath too long or in water that is too hot

  • Pick up sections in a timelier manner or reduce temperature in water bath

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